Endocrine Abstracts

Aim: Studying of influence of various doses of cabergoline in dynamics of 6, 12 and 24 months of treatment on level of blood serum soluble apoptosis markers P53, Bcl-2 and TNF-α in patients with IPA.Materials and methods: One hundred and twenty-seven patients with IPA (38 men, 89 women) were observed, among them 65 (51.2%) with microadenoma and 62 (48.8%) with macroadenoma/ patients were at the age from 35 till 60 years.Patients with pituitar...

Aim: To study complications in patients with acromegaly receiving somatostatin after radiotherapy.Materials and methods: We examined 16 patients with mean disease duration 8.5±4.2 years (mean age 41.5±5.6 years) receiving distant gamma-therapy in the total dose of 60 Gy. The patients were divided into two groups: eight patients receiving somatostatin in the dose of 0.5 mg thrice a day and symptomatic therapy for 2 months were included into the ...

Aim: To study clinical–epidemiological peculiarities of diabetic macroangiopathies in diabetes mellitus (DM) and diabetes insipidus (DI) combination.Materials and methods: We examined 2208 cases of DI registered in the RUz in 2006–2010, 106 DM–DI combinations among them. DM–DI combination prevalence, calculated for 100 000 of adult and infant population, was assessed analysis of data on patients registered at the endocrine ambulances....

Aim: To evaluate influence of cabergoline on LAO and BAS processes in treatment of patients with NFPA.Materials and methods: We included 64 patients with NFPA in the study. Mean age was 43.6±3.84 years (range 30–55 years). Of 64 patients 26 (40.6%) were men and 38 (59.4%) were women. Duration of the disease from diagnosis based on MRI constituted 1–15 years. Severity criteria used in the evaluation were LH, FSH and prolactin (PRL) growth a...

Aim: To study character of macrovascular complications in combination of diabetes mellitus (DM) and diabetes insipidus (DI).Materials and methods: Within the period from 2006 to 2010, we examined 2208 cases of DI among them 106 DM–DI combinations. The patients had their endocrine and neurologic statuses assessed with blood and urine density investigation, including complete urinalysis and Zimnitskyi urine count, RIA and measurement of pituitary horm...

Aim: To study the effectiveness of metformin in treatment of polycystic ovaries syndrome (PCOS) in women of birthing age.Materials and methods: We followed 31 women with PCOS. Mean age of patients was 29.8 years old. All patients were evaluated for hormones levels (LH, FSH, TSH, estradiol, progesterone, testosterone, prolactin, coritsole, free thyroxine, dehydroepiahndrostendione etc.), glucose tolerance test, lipids profile, uterus and ovaries ultrasono...